Mesotherapy for knee joint pain

Mesotherapy is the injection of active substances into the surface layer of the skin. This method allows a slower spread, higher levels, and longer lasting effects of drugs in the tissues underlying the site of injection (skin, muscle, and joint) compared with those following intramuscular injection. This technique is useful when a local pharmacological effect is required and relatively high doses of drug in the systemic circulation are not. Mesotherapy should only be undertaken following a complete clinical workup and subsequent diagnosis.

Mesotherapy is both effective and safe for the treatment of patients with OA. Mesotherapy is included as an ancillary treatment in the management of localized pain in rehabilitation. Regardless of mesotherapy technique, its effects on pain can vary, depending on the points and drugs, for which there remain no definitive treatment protocols. 


  • For Knee Pain: an improvement in pain and function in patients who were treated with mesotherapy and concluded that this approach is safe and effective in OA
  • Back Pain Treatment: It is a simple, cost-effective, and promising method for treating Back pain.
  • Neck pain: Mesotherapy is also applied in cervical pain under acute and chronic conditions. Neck pain is a major public health problem with a high prevalence in the general population. In patients with chronic neck pain and showed a reduction of neck pain at the end of the therapy sessions respect baseline.
    In conclusion, mesotherapy is a good option in rehabilitation field for musculoskeletal pain with good advantages and few or no side effects.